I've been on Arimidex for a couple of years and recently started taking St. John's Wort as I'd been feeling pretty miserable without any specific reason. I Googled first and found a very old thread about it on this site, but wondered if anyone knows anything about any contraindications as regards oestrogen. The upside is that it does seem to have improved my mood, but I'm getting a bit worried about using it long-term. Does anyone else have any experience with it? Thanks.
I think the problem is, although St John's Wort is seen as a "natural" remedy for depression, there are interactions with other drugs and it can cause thinning of the blood. To be on the safe side, I would definitely ask your GP/onc whoever if it is safe. There have been some recent studies that suggest it can have some side effects if taken with the wrong drugs.